Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12634440 | 0.89 | SCN8A (0.39) | ALOX5PTGS2LIPGALDH1A1CYP3A4 | |
| SCHEMBL13552191 | 0.84 | MEN1 (0.36) | ALOX5PTGS2CYP3A4MEN1LMNA | |
| SCHEMBL17610553 | 0.81 | MAPK1 (0.46) | PTGS2ALDH1A1CYP3A4MEN1USP2 | |
| SCHEMBL73774 | 0.81 | LTB4R (0.48) | ALOX5PTGS2LTB4RLTB4R2CYP2C9 | |
| SCHEMBL14092078 | 0.79 | TYR (0.39) | ALOX5ALDH1A1CYP3A4MEN1USP2 | |
| SCHEMBL1031044 | 0.79 | LTB4R (0.53) | ALOX5PTGS2LIPGPPARAPPARG | |
| SCHEMBL9221616 | 0.79 | PPARA (0.40) | ALOX5PTGS2LIPGALDH1A1CYP3A4 | |
| SCHEMBL13506923 | 0.78 | ALOX5 (0.40) | ALOX5PTGS2LIPGCYP3A4PPARA | |
| SCHEMBL12134893 | 0.77 | SLC13A5 (0.41) | ALOX5PTGS2LIPGALDH1A1CYP3A4 | |
| SCHEMBL2158581 | 0.77 | PPARA (0.41) | ALOX5ALDH1A1CYP3A4LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111465589-B | Compound having fluorene skeleton and method for producing same | 帝人株式会社 | 2024-01-05 | — | — | CN | disclosed |
| US-11339249-B2 | Compound having fluorene skeleton, and method for manufacturing same | TEIJIN LIMITED (JP) | 2022-05-24 | — | — | US | disclosed |
| EP-3747856-A1 | COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME | Teijin Limited (JP) | 2020-12-09 | — | — | EP | disclosed |
| US-20200354517-A1 | COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME | TEIJIN LIMITED (JP) | 2020-11-12 | — | — | US | disclosed |
| WO-2020085222-A1 | CRYSTAL OF COMPOUND HAVING FLUORENE SKELETON AND METHOD FOR PRODUCING SAME | 帝人株式会社 | 2020-04-30 | — | — | WO | disclosed |
| WO-2019151264-A1 | COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME | 帝人株式会社 | 2019-08-08 | — | — | WO | disclosed |
| US-8841491-B2 | Method for producing fluorene derivative | TAOKA CHEMICAL CO., LTD. (JP) | 2014-09-23 | — | — | US | disclosed |
| CN-102388012-A | Method for producing fluorene derivative | TAOKA CHEMICAL CO LTD | 2012-03-21 | — | — | CN | disclosed |
| EP-2420485-A1 | METHOD FOR PRODUCING FLUORENE DERIVATIVE | Taoka Chemical Co., Ltd. (JP) | 2012-02-22 | — | — | EP | disclosed |
| US-20120029244-A1 | METHOD FOR PRODUCING FLUORENE DERIVATIVE | TAOKA CHEMICAL CO., LTD. (JP) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354517-A1 | COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME | RFT1, AFF1, RER1 | ALOX5 2264/4885PTGS2 3096/4885LIPG 4867/4885 |
| US-20120029244-A1 | METHOD FOR PRODUCING FLUORENE DERIVATIVE | ADH1A, AFF2, AFF1 | ALOX5 751/4885PTGS2 1409/4885LIPG 2812/4885 |
| US-11339249-B2 | Compound having fluorene skeleton, and method for manufacturing same | RFT1, AFF1, RER1 | ALOX5 2264/4885PTGS2 3096/4885LIPG 4867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.