Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 7/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GCK | P35557 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30359932 | 1.00 | SGMS2 (0.54) | SGMS2HTR1ADRD2ALDH1A1POLB | |
| SCHEMBL30359922 | 0.85 | HTR1A (0.56) | SGMS2HTR1ADRD2ALDH1A1POLB | |
| SCHEMBL21585887 | 0.85 | HTR1A (0.56) | SGMS2HTR1ADRD2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL28500564 | 0.83 | KLK8 (0.55) | SGMS2HTR1ADRD2ALDH1A1POLB | |
| SCHEMBL8034556 | 0.78 | PARP1 (0.61) | SGMS2HTR1ADRD2ALDH1A1POLB | |
| SCHEMBL15084393 | 0.75 | HTR1A (0.61) | HTR1ADRD2ALDH1A1POLBGCK | |
| SCHEMBL29957711 | 0.74 | LIPE (0.69) | SGMS2HTR1ADRD2ALDH1A1POLB | |
| SCHEMBL14678467 | 0.74 | HTR1A (0.60) | SGMS2HTR1ADRD2ALDH1A1POLB | |
| SCHEMBL15088051 | 0.73 | ALDH1A1 (0.53) | SGMS2HTR1ADRD2ALDH1A1LRRK2 | |
| SCHEMBL13359016 | 0.73 | HTR1A (0.55) | HTR1ADRD2ALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236433-B | Novel compounds | 国家医疗保健研究所 | 2023-04-04 | — | — | CN | disclosed |
| CN-112236433-A | Novel compounds | 国家医疗保健研究所 | 2021-01-15 | — | — | CN | disclosed |
| WO-2019234075-A1 | NOVEL BENZIMIDAMIDES COMPOUNDS COMPRISING AN OXABORININ RING | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2019-12-12 | — | — | WO | disclosed |