Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903036 | 0.69 | LMNA (0.34) | LMNARECQL | |
| SCHEMBL903069 | 0.67 | GAA (0.33) | LMNARECQL | |
| SCHEMBL23062876 | 0.64 | BRD4 (0.40) | LMNARECQL | |
| SCHEMBL12021938 | 0.62 | SMN1; SMN2 (0.34) | LMNARECQL | |
| SCHEMBL470293 | 0.62 | KDM4E (0.31) | — | |
| SCHEMBL8303828 | 0.61 | ALDH1A1 (0.44) | LMNARECQL | |
| SCHEMBL903089 | 0.60 | GAA (0.34) | LMNARECQL | |
| SCHEMBL6889091 | 0.60 | RECQL (0.43) | LMNARECQL | |
| SCHEMBL903112 | 0.59 | TSHR (0.32) | — | |
| SCHEMBL902650 | 0.59 | GAA (0.33) | LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807269-A1 | NEW ISOXAZOLYL ETHER DERIVATIVES AS GABA A ALPHA5 PAM | F. Hoffmann-La Roche AG (CH) | 2021-04-21 | — | — | EP | disclosed |
| WO-2019238633-A1 | NEW ISOXAZOLYL ETHER DERIVATIVES AS GABA A ALPHA5 PAM | F. HOFFMANN-LA ROCHE AG (CH) | 2019-12-19 | — | — | WO | disclosed |