Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903086 | 0.72 | LMNA (0.34) | LMNARECQLMEN1GAAKMT2A | |
| SCHEMBL12021938 | 0.69 | SMN1; SMN2 (0.34) | LMNARECQLMEN1GAAKMT2A | |
| SCHEMBL21590983 | 0.69 | LMNA (0.32) | LMNARECQL | |
| SCHEMBL23062876 | 0.67 | BRD4 (0.40) | LMNARECQLMEN1GAAKMT2A | |
| SCHEMBL903069 | 0.65 | GAA (0.33) | LMNARECQLMEN1GAAKMT2A | |
| SCHEMBL6889091 | 0.63 | RECQL (0.43) | LMNARECQLMEN1GAAKMT2A | |
| SCHEMBL470293 | 0.62 | KDM4E (0.31) | MEN1KMT2AHTT | |
| SCHEMBL223413 | 0.62 | GAA (0.49) | LMNAMEN1GAAKMT2A | |
| SCHEMBL2807054 | 0.60 | LMNA (0.54) | LMNARECQLMEN1GAAKMT2A | |
| SCHEMBL4795046 | 0.60 | GAA (0.41) | LMNARECQLMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044531-A1 | NOVEL PIPERAZINE ANALOGS WITH SUBSTITUTED HETEROARYL GROUPS AS BROAD-SPECTRUM INFLUENZA ANTIVIRALS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-04-05 | — | — | WO | disclosed |