Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17378987 | 0.86 | MAPT (0.38) | MAPTALDH1A1PKMMAOBPTPN1 | |
| SCHEMBL21591553 | 0.81 | CYP11B1 (0.62) | ALDH1A1MAOBPTPN1CYP11B1CYP11B2 | |
| SCHEMBL21591546 | 0.77 | CYP11B1 (0.64) | MAPTALDH1A1MAOBCYP11B1CYP11B2 | |
| SCHEMBL29591394 | 0.76 | PTPN1 (0.46) | MAPTALDH1A1MAOBPTPN1GAA | |
| SCHEMBL9075843 | 0.76 | MAOB (0.71) | ALDH1A1MAOBPTPN1CYP11B1CYP11B2 | |
| SCHEMBL21954375 | 0.76 | PTPN1 (0.46) | MAPTALDH1A1MAOBPTPN1GAA | |
| SCHEMBL21591476 | 0.75 | CYP11B1 (0.37) | ALDH1A1MAOBPTPN1CYP11B1CYP11B2 | |
| SCHEMBL28477936 | 0.75 | ALDH1A1 (0.47) | MAPTALDH1A1PKMMAOBPTPN1 | |
| SCHEMBL28990341 | 0.75 | ALDH1A1 (0.47) | MAPTALDH1A1PKMMAOBPTPN1 | |
| SCHEMBL1530595 | 0.74 | MAPT (0.39) | MAPTALDH1A1PKMMAOBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12162863-B2 | Modulators of stimulator of interferon genes (STING) | Ryvu Therapeutics S.A. (PL) | 2024-12-10 | — | — | US | disclosed |
| US-20220402898-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2022-12-22 | — | — | US | disclosed |
| EP-3807264-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2021-04-21 | — | — | EP | disclosed |
| WO-2019238786-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2019-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12162863-B2 | Modulators of stimulator of interferon genes (STING) | STING1, IRF3, CGAS | MAPT 1787/4885ALDH1A1 4462/4885PKM 3137/4885 |
| US-20220402898-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | STING1, IRF3, CGAS | MAPT 1787/4885ALDH1A1 4462/4885PKM 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.