Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19231173 | 0.93 | KDM4E (0.51) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4386263 | 0.82 | KDM4E (0.72) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9446986 | 0.81 | KDM4E (0.63) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL625749 | 0.76 | NSD2 (0.62) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL15516799 | 0.75 | G6PD (0.45) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL20193999 | 0.74 | KDM4E (0.48) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL20589073 | 0.74 | NSD2 (0.60) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL9447016 | 0.74 | MEN1 (0.63) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9447019 | 0.73 | KDM4E (0.57) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| 8-Aminoquinoline SCHEMBL159694 | 0.72 | LMNA (0.61) | KDM4EMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019238817-A1 | BIFUNCTIONAL MOLECULES FOR TARGETING RPN11 | UNIVERSITY OF DUNDEE (GB) | 2019-12-19 | — | — | WO | disclosed |