Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.65 |
| ▸ | HTR1A | P08908 | 7/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.50 |
| ▸ | HTR3B | O95264 | 3/20 | 0.50 |
| ▸ | HTR3A | P46098 | 3/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10198628 | 0.86 | PIM1 (0.50) | HTR7HTR1AADRB1HTR3EHTR3B | |
| SCHEMBL15244929 | 0.82 | ADRB1 (0.53) | HTR7HTR1AADRB1HTR2CHTR3E | |
| SCHEMBL15274976 | 0.81 | PIM1 (0.46) | HTR7HTR1AADRB1HTR3EHTR3B | |
| SCHEMBL1914606 | 0.79 | HTR7 (1.00) | HTR7HTR1AADRB1HTR2CHTR3E | |
| SCHEMBL30022113 | 0.79 | HTR7 (1.00) | HTR7HTR1AADRB1HTR2CHTR3E | |
| Hydrochloric Acid SCHEMBL29157433 | 0.78 | HTR7 (0.96) | HTR7HTR1AADRB1HTR2CHTR3E | |
| Hydrochloric Acid SCHEMBL6786785 | 0.78 | HTR7 (0.96) | HTR7HTR1AADRB1HTR2CHTR3E | |
| SCHEMBL30146627 | 0.78 | HTR7 (0.96) | HTR7HTR1AADRB1HTR2CHTR3E | |
| SCHEMBL13118661 | 0.77 | HTR7 (0.76) | HTR7HTR1AADRB1HTR2CHTR3E | |
| SCHEMBL15577989 | 0.77 | HTR7 (1.00) | HTR7HTR1AADRB1HTR2CHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160287586-A1 | COMPOUNDS AND METHODS FOR TREATING CANDIDIASIS AND ASPERGILLUS INFECTIONS | CELLCEUTIX CORPORATION | 2016-10-06 | — | — | US | disclosed |
| US-20160287586-A1 | COMPOUNDS AND METHODS FOR TREATING CANDIDIASIS AND ASPERGILLUS INFECTIONS | CELLCEUTIX CORPORATION | 2016-10-06 | — | — | US | disclosed |
| US-20120115877-A1 | Facially Amphiphilic Compounds, Compositions, And Uses Thereof In Treating Cancer | POLYMEDIX, INC. (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120115877-A1 | Facially Amphiphilic Compounds, Compositions, And Uses Thereof In Treating Cancer | POLYMEDIX, INC. (US) | 2012-05-10 | — | — | US | disclosed |
| WO-2012027230-A1 | FACIALLY AMPHIPHILIC COMPOUNDS, COMPOSITIONS, AND USES THEREOF IN TREATING CANCER | POLYMEDIX, INC. (US) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115877-A1 | Facially Amphiphilic Compounds, Compositions, And Uses Thereof In Treating Cancer | LIPA, ABHD16A, SGMS1 | HTR7 2645/4885HTR1A 4190/4885ADRB1 4085/4885 |
| US-20160287586-A1 | COMPOUNDS AND METHODS FOR TREATING CANDIDIASIS AND ASPERGILLUS INFECTIONS | ERG28, DPM1, MANBA | HTR7 4794/4885HTR1A 4813/4885ADRB1 3357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.