Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 10/20 | 0.96 |
| ▸ | HTR1A | P08908 | 8/20 | 0.96 |
| ▸ | TP53 | P04637 | 4/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.69 |
| ▸ | USP2 | O75604 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.66 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.66 |
| ▸ | HTR3B | O95264 | 2/20 | 0.66 |
| ▸ | HTR3A | P46098 | 2/20 | 0.66 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.66 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30022113 | 0.98 | HTR7 (1.00) | HTR7HTR1ATP53CYP1A2CYP2D6 | |
| SCHEMBL1914606 | 0.98 | HTR7 (1.00) | HTR7HTR1ATP53CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL29157433 | 0.96 | HTR7 (0.96) | HTR7HTR1ATP53CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL6786785 | 0.96 | HTR7 (0.96) | HTR7HTR1ATP53CYP1A2CYP2D6 | |
| SCHEMBL13118661 | 0.85 | HTR7 (0.76) | HTR7HTR1ATP53CYP1A2CYP2D6 | |
| SCHEMBL15577989 | 0.85 | HTR7 (1.00) | HTR7HTR1ATP53CYP1A2CYP2D6 | |
| SCHEMBL15538190 | 0.85 | HTR7 (0.75) | HTR7HTR1ATP53CYP1A2CYP2D6 | |
| SCHEMBL13118660 | 0.83 | HTR7 (0.81) | HTR7HTR1ATP53CYP1A2CYP2D6 | |
| SCHEMBL27497441 | 0.81 | HTR1A (0.70) | HTR7HTR1ATP53CYP1A2CYP2D6 | |
| SCHEMBL1359864 | 0.81 | ADRB1 (0.76) | HTR7HTR1ATP53CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179059-A1 | ANTICANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-06-05 | — | — | US | disclosed |
| US-12162870-B2 | Anticancer compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-12-10 | — | — | US | disclosed |
| US-20230025178-A1 | ANTICANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179059-A1 | ANTICANCER COMPOUNDS | BET1, BRD4, BICRA | HTR7 3578/4885HTR1A 4383/4885TP53 46/4885 |
| US-20230025178-A1 | ANTICANCER COMPOUNDS | BET1, BRD4, BICRA | HTR7 3578/4885HTR1A 4383/4885TP53 46/4885 |
| US-12162870-B2 | Anticancer compounds | BET1, BRD4, BICRA | HTR7 3578/4885HTR1A 4383/4885TP53 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.