Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25707182 | 0.80 | TRPV4 (0.45) | TRPV4PLA2G7 | |
| SCHEMBL24816739 | 0.77 | TRPV4 (0.42) | TRPV4 | |
| SCHEMBL20546963 | 0.77 | TRPV4 (0.42) | TRPV4HTR2APLA2G7 | |
| SCHEMBL20860169 | 0.77 | HTR2A (0.40) | HTR2A | |
| SCHEMBL24816742 | 0.75 | TRPV4 (0.40) | TRPV4PLA2G7 | |
| SCHEMBL2796067 | 0.74 | TRPV4 (0.47) | TRPV4 | |
| SCHEMBL24167714 | 0.73 | KDM4E (0.45) | TRPV4EGLN2 | |
| SCHEMBL20853755 | 0.72 | HTR2A (0.34) | HTR2A | |
| SCHEMBL30933437 | 0.72 | ALDH1A1 (0.40) | TRPV4EGLN2 | |
| SCHEMBL21596788 | 0.72 | TRPV4 (0.48) | TRPV4EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163031-A1 | BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES | INSILICO MEDICINE IP LIMITED (HK) | 2025-05-22 | — | — | US | disclosed |
| US-12162862-B2 | Beta-lactam derivatives for the treatment of diseases | INSILICO MEDICINE IP LIMITED (HK) | 2024-12-10 | — | — | US | disclosed |
| CN-118019737-A | Beta-lactam derivatives for the treatment of diseases | 英矽智能科技知识产权有限公司 | 2024-05-10 | — | — | CN | disclosed |
| EP-4359405-A1 | BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES | Insilico Medicine IP Limited (HK) | 2024-05-01 | — | — | EP | disclosed |
| US-20240116899-A1 | BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES | INSILICO MEDICINE IP LIMITED (HK) | 2024-04-11 | — | — | US | disclosed |
| US-11834440-B2 | Beta-lactam derivatives for the treatment of diseases | INSILICO MEDICINE IP LIMITED (HK) | 2023-12-05 | — | — | US | disclosed |
| US-11834440-B2 | Beta-lactam derivatives for the treatment of diseases | INSILICO MEDICINE IP LIMITED (HK) | 2023-12-05 | — | — | US | disclosed |
| US-11834440-B2 | Beta-lactam derivatives for the treatment of diseases | INSILICO MEDICINE IP LIMITED (HK) | 2023-12-05 | — | — | US | disclosed |
| US-20230192667-A1 | BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES | INSILICO MEDICINE IP LIMITED (HK) | 2023-06-22 | — | — | US | disclosed |
| US-20230192667-A1 | BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES | INSILICO MEDICINE IP LIMITED (HK) | 2023-06-22 | — | — | US | disclosed |
| WO-2022268179-A1 | BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES | INSILICO MEDICINE IP LIMITED (CN) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022268179-A1 | BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES | INSILICO MEDICINE IP LIMITED (CN) | 2022-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192667-A1 | BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES | QPCT, QPCTL, BCAT1 | TRPV4 4779/4885HTR2A 3214/4885PLA2G7 1290/4885 |
| US-20240116899-A1 | BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES | QPCT, QPCTL, BCAT1 | TRPV4 4779/4885HTR2A 3214/4885PLA2G7 1290/4885 |
| US-12162862-B2 | Beta-lactam derivatives for the treatment of diseases | QPCT, QPCTL, BCAT1 | TRPV4 4779/4885HTR2A 3214/4885PLA2G7 1290/4885 |
| US-11834440-B2 | Beta-lactam derivatives for the treatment of diseases | QPCT, QPCTL, BCAT1 | TRPV4 4779/4885HTR2A 3214/4885PLA2G7 1290/4885 |
| US-20250163031-A1 | BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES | QPCT, QPCTL, BCAT1 | TRPV4 4779/4885HTR2A 3214/4885PLA2G7 1290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.