SCHEMBL29652513

SCHEMBL29652513

CCc1ccc(OC)c(S(=O)(=O)N(OCc2ccc(OC)cc2OC)c2noc3c(-c4cnn(C)c4)cccc23)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CCNA2 P20248 2/20 0.36
▸ CDK2 P24941 2/20 0.36
▸ TTK P33981 2/20 0.36
▸ KDM4E B2RXH2 1/20 0.34
▸ POLB P06746 1/20 0.34
▸ BRD4 O60885 3/20 0.33
▸ KDR P35968 2/20 0.33
▸ FGFR3 P22607 1/20 0.33
▸ KAT7 O95251 4/20 0.32
▸ KAT6A Q92794 4/20 0.32
▸ KAT6B Q8WYB5 3/20 0.32
▸ KAT5 Q92993 2/20 0.32
▸ KAT8 Q9H7Z6 2/20 0.32
▸ ALPL P05186 1/20 0.32
▸ LOXL2 Q9Y4K0 2/20 0.32
▸ PTGDR2 Q9Y5Y4 1/20 0.31
▸ CSF1R P07333 2/20 0.31
▸ HTR6 P50406 1/20 0.31
▸ LRRK2 Q5S007 1/20 0.31
▸ PDGFRB P09619 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28512950 1.00 CCNA2 (0.36) CCNA2CDK2TTKKDM4EPOLB
SCHEMBL29652454 0.84 MAPT (0.36) POLBKAT7KAT6AKAT6BKAT5
SCHEMBL21596809 0.84 MAPT (0.36) POLBKAT7KAT6AKAT6BKAT5
SCHEMBL28906747 0.84 ALDH1A1 (0.32) POLBBRD4KAT7KAT6AKAT6B
SCHEMBL29652522 0.84 ALDH1A1 (0.32) POLBBRD4KAT7KAT6AKAT6B
SCHEMBL28507830 0.83 KAT7 (0.33) BRD4KAT7KAT6AKAT6BKAT5
SCHEMBL29652540 0.83 KAT7 (0.33) BRD4KAT7KAT6AKAT6BKAT5
SCHEMBL31605552 0.82 MAPT (0.38) KDM4EKAT7KAT6AKAT6BKAT5
SCHEMBL21596821 0.82 MAPT (0.38) KDM4EKAT7KAT6AKAT6BKAT5
SCHEMBL21596863 0.81 KDM4E (0.36) CCNA2CDK2TTKKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 — — US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 — — US disclosed
CN-112334466-B Compounds of formula (I) CTXT私人有限公司 2025-05-30 — — CN disclosed
EP-4335439-A2 COMPOUNDS CTXT PTY LTD (AU) 2024-03-13 — — EP disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 CCNA2 3942/4885CDK2 2456/4885TTK 4366/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B CCNA2 2639/4885CDK2 3792/4885TTK 3234/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 CCNA2 3939/4885CDK2 2453/4885TTK 4365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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