Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | TERT | O14746 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 4/20 | 0.45 |
| ▸ | CASP7 | P55210 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596926 | 0.81 | MEN1 (0.48) | KMT2AMEN1LMNAALDH1A1TP53 | |
| SCHEMBL21596785 | 0.74 | KDM4E (0.47) | KMT2AMEN1TERTABCB11LMNA | |
| SCHEMBL29652574 | 0.74 | KDM4E (0.47) | KMT2AMEN1TERTABCB11LMNA | |
| SCHEMBL21596941 | 0.74 | NPC1 (0.48) | LMNABLMHSD17B10TP53CYP3A4 | |
| SCHEMBL10251292 | 0.72 | NR4A2 (0.53) | KMT2AMEN1TERTABCB11LMNA | |
| SCHEMBL30513775 | 0.72 | MAP4K4 (0.72) | KMT2AMEN1TERTABCB11LMNA | |
| SCHEMBL19122690 | 0.72 | KMT2A (0.51) | KMT2AMEN1TERTABCB11LMNA | |
| SCHEMBL21596925 | 0.72 | DYRK1A (0.44) | KMT2AMEN1LMNAALDH1A1TYMS | |
| SCHEMBL21596857 | 0.71 | HTR3A (0.47) | KMT2AMEN1TERTABCB11LMNA | |
| SCHEMBL439655 | 0.70 | ALDH1A1 (0.80) | KMT2AMEN1TERTABCB11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |