SCHEMBL21596785

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29652574	1.00	KDM4E (0.47)	KDM4EALDH1A1HPGDMEN1KMT2A
	SCHEMBL21596857	0.87	HTR3A (0.47)	KDM4EALDH1A1HPGDMEN1KMT2A
	SCHEMBL19142570	0.82	KDM4E (0.51)	KDM4EALDH1A1HPGDMEN1KMT2A
	SCHEMBL6955470	0.81	ALDH1A1 (0.47)	KDM4EALDH1A1HPGDMEN1KMT2A
	SCHEMBL29652612	0.81	ALDH1A1 (0.47)	KDM4EALDH1A1HPGDMEN1KMT2A
	SCHEMBL31432494	0.76	ROCK1 (0.41)	MAP4K4
	SCHEMBL12044601	0.75	RAB9A (0.41)	KDM4EALDH1A1HPGDMEN1KMT2A
	SCHEMBL21596922	0.74	KMT2A (0.50)	KDM4EALDH1A1HPGDMEN1KMT2A
	SCHEMBL21609212	0.74	EPHX2 (0.46)	KDM4ELMNABLMNPC1TP53
	SCHEMBL29652544	0.74	EPHX2 (0.46)	KDM4ELMNABLMNPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.