Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SCN4A | P35499 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596926 | 0.78 | MEN1 (0.48) | NPC1RAB9ALMNATP53CYP1A2 | |
| SCHEMBL29652544 | 0.74 | EPHX2 (0.46) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL21596922 | 0.74 | KMT2A (0.50) | NPC1RAB9ALMNATP53CYP1A2 | |
| SCHEMBL21609212 | 0.74 | EPHX2 (0.46) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL4271192 | 0.71 | NR4A2 (0.51) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL30513837 | 0.71 | MAP4K4 (0.54) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL439264 | 0.69 | HSD17B10 (0.64) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL2145154 | 0.68 | MEN1 (0.47) | RAB9AKDM4EPIM1DYRK1A | |
| SCHEMBL21596925 | 0.68 | DYRK1A (0.44) | NPC1RAB9ALMNASMN1; SMN2IP6K1 | |
| SCHEMBL440348 | 0.68 | NPC1 (0.44) | NPC1RAB9AGMNNUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |