Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596932 | 0.81 | DCPS (0.51) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL21596931 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL1782232 | 0.74 | KDR (0.46) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL21596900 | 0.71 | ALDH1A1 (0.44) | ALDH1A1KDM4ETLR8DHFRLMNA | |
| SCHEMBL8294968 | 0.71 | DCPS (0.69) | DHFRDCPS | |
| SCHEMBL21596923 | 0.71 | ELANE (0.35) | ALDH1A1KDM4EMEN1KMT2ADHFR | |
| SCHEMBL15293089 | 0.70 | DCPS (0.50) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7930788 | 0.68 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL21596915 | 0.68 | PARP1 (0.41) | GAADHFR | |
| SCHEMBL21596942 | 0.68 | BACE1 (0.40) | CA1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |