Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | DCPS | Q96C86 | 9/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596932 | 0.75 | DCPS (0.51) | ELANEDCPSALDH1A1MEN1KMT2A | |
| SCHEMBL21596849 | 0.74 | KDR (0.46) | LMNA | |
| SCHEMBL4367263 | 0.72 | ACHE (0.39) | TYMS | |
| SCHEMBL21596935 | 0.71 | ALDH1A1 (0.44) | DCPSALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL21596919 | 0.69 | TYMS (0.32) | TYMSALDH1A1KDM4E | |
| SCHEMBL30601048 | 0.68 | LMNA (0.39) | TYMSALDH1A1MEN1HTTKMT2A | |
| SCHEMBL21596915 | 0.68 | PARP1 (0.41) | ELANEDHFR | |
| SCHEMBL21596942 | 0.68 | BACE1 (0.40) | TYMS | |
| SCHEMBL4038330 | 0.67 | CD44 (0.43) | TYMSALDH1A1TSHRHTTNPSR1 | |
| SCHEMBL30645137 | 0.67 | CD44 (0.43) | TYMSALDH1A1TSHRHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |