Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | CASP7 | P55210 | 1/20 | 0.64 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439632 | 0.88 | NR4A2 (0.54) | HSD17B10ALDH1A1CASP1CASP7NCF1 | |
| SCHEMBL437286 | 0.81 | HSD17B10 (0.71) | HSD17B10ALDH1A1CASP1CASP7NCF1 | |
| SCHEMBL436437 | 0.79 | MCHR1 (0.51) | HSD17B10ALDH1A1CASP1CASP7NPC1 | |
| SCHEMBL3471999 | 0.78 | ALDH1A1 (1.00) | HSD17B10ALDH1A1CASP1CASP7NCF1 | |
| SCHEMBL27890180 | 0.78 | ALDH1A1 (0.62) | HSD17B10ALDH1A1CASP1CASP7NCF1 | |
| SCHEMBL4748820 | 0.77 | ALDH1A1 (0.66) | HSD17B10ALDH1A1CASP1CASP7NCF1 | |
| SCHEMBL439655 | 0.77 | ALDH1A1 (0.80) | HSD17B10ALDH1A1CASP1CASP7NCF1 | |
| SCHEMBL437638 | 0.76 | MCHR1 (0.59) | HSD17B10ALDH1A1CASP1CASP7NCF1 | |
| SCHEMBL22828432 | 0.75 | POLB (0.51) | HSD17B10ALDH1A1NPC1RAB9AALOX15 | |
| SCHEMBL4271192 | 0.75 | NR4A2 (0.51) | HSD17B10ALDH1A1CASP1CASP7NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |