Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | CPN1 | P15169 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | VNN1 | O95497 | 2/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21606269 | 0.82 | HPGD (0.47) | MEN1KMT2A | |
| SCHEMBL18440594 | 0.81 | CCR5 (0.40) | PIK3CDCPN1CPB2LMNAL3MBTL3 | |
| SCHEMBL13900240 | 0.81 | PIN1 (0.42) | PIN1PIK3CD | |
| SCHEMBL13900622 | 0.78 | PIN1 (0.41) | PIN1PIK3CDALDH1A1 | |
| SCHEMBL18440833 | 0.75 | PIK3CD (0.35) | PIK3CDCPN1CPB2 | |
| SCHEMBL21606270 | 0.75 | SLC6A4 (0.46) | PIN1PIK3CD | |
| SCHEMBL27176071 | 0.74 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL27849291 | 0.73 | OPRM1 (0.55) | CHRM2CHRM3OPRM1 | |
| SCHEMBL1061775 | 0.72 | L3MBTL3 (0.37) | LMNAL3MBTL3PDK2ALDH1A1MEN1 | |
| SCHEMBL3831586 | 0.72 | DPP4 (0.43) | LMNAL3MBTL3PDK2VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810614-A1 | BRIDGED COMPOUNDS AS AGONISTS OF THE MUSCARINIC M1 AND/OR M4 RECEPTOR | Heptares Therapeutics Limited (GB) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243851-A1 | BRIDGED COMPOUNDS AS AGONISTS OF THE MUSCARINIC M1 AND/OR M4 RECEPTOR | HEPTARES THERAPEUTICS LIMITED (GB) | 2019-12-26 | — | — | WO | disclosed |