SCHEMBL4905489

SCHEMBL4905489

CC(C)c1ccc(-c2ccc[c]c2C(C)C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.39
LMNA P02545 2/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
KMT2A Q03164 1/20 0.39
BRD4 O60885 1/20 0.34
CREBBP Q92793 1/20 0.34
NOTUM Q6P988 2/20 0.33
RAB9A P51151 4/20 0.33
PAX8 Q06710 1/20 0.33
NOD2 Q9HC29 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ERBB2 P04626 1/20 0.33
NPC1 O15118 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
TP53 P04637 1/20 0.33
DGAT1 O75907 1/20 0.32
ERN1 O75460 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2160199 0.85 CDC25A (0.38) MAPTMEN1KMT2ANPSR1HPGD
SCHEMBL8212159 0.84 PTPRC (0.35) MAPTLMNAMEN1KMT2ARAB9A
SCHEMBL10833643 0.78 SIGMAR1 (0.33) MAPTRAB9ANPC1NISCH
SCHEMBL5674435 0.77 ERN1 (0.38) MAPTLMNAMEN1USP2KMT2A
SCHEMBL11032010 0.77 MAPT (0.40) MAPTLMNAMEN1USP2KMT2A
SCHEMBL11032013 0.73 MAPT (0.45) MAPTLMNAMEN1USP2KMT2A
SCHEMBL3938740 0.73 ACACB (0.37) MAPTLMNAMEN1USP2KMT2A
SCHEMBL10878358 0.71 MAPT (0.50) MAPTLMNAMEN1USP2KMT2A
SCHEMBL16105728 0.70 KIF11 (0.35) MAPTLMNAMEN1USP2KMT2A
SCHEMBL8088785 0.70 LMNA (0.38) MAPTLMNAMEN1USP2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080028985-A1 Water-Dispersed Slurry Coating TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2008-02-07 US disclosed