Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10623223 | 0.96 | PTGS2 (0.38) | PDCD1CD274ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL2565144 | 0.84 | TDP1 (0.35) | ALDH1A1HPGDMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL7707290 | 0.83 | ALDH1A1 (0.38) | ALDH1A1MAPK1PTGS2SMN1; SMN2MEN1 | |
| SCHEMBL7700044 | 0.83 | GSTP1 (0.49) | PTGS2SMN1; SMN2NPC1TSHRRAB9A | |
| SCHEMBL22115865 | 0.83 | — | — | |
| SCHEMBL2014605 | 0.81 | PTGS2 (0.42) | PTGS2SLC6A4 | |
| SCHEMBL7459931 | 0.81 | ALDH1A1 (0.39) | ALDH1A1HSD17B10MEN1KMT2ANPC1 | |
| SCHEMBL6823830 | 0.81 | PTGS2 (0.42) | ALDH1A1HSD17B10HPGDPTGS2SLC6A4 | |
| SCHEMBL8880561 | 0.81 | MAPT (0.39) | ALDH1A1HSD17B10MAPK1AKT1SMN1; SMN2 | |
| SCHEMBL3537988 | 0.79 | ACHE (0.41) | ALDH1A1HPGDSMN1; SMN2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108750-A | Method for preparing homoallylsilane compound | 中国科学院大连化学物理研究所 | 2024-05-31 | — | — | CN | claimed |
| CN-116102888-A | Damping vibration-absorbing silicone rubber composition and preparation method thereof | 安徽东爵有机硅有限公司 | 2023-05-12 | — | — | CN | claimed |
| US-10076517-B2 | Methods and pharmaceutical compositions for the treatment of fibrosis | INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE KA RECHERCHE MÉDICALE (FR) | 2018-09-18 | — | — | US | claimed |
| JP-6008256-B2 | — | ネピュレ株式会社 | 2016-10-19 | — | — | JP | claimed |
| CN-102459167-B | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV | 2015-04-01 | — | — | CN | claimed |
| EP-2421825-B9 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-20 | — | — | EP | claimed |
| US-8691805-B2 | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA, NV (BE) | 2014-04-08 | — | — | US | claimed |
| EP-2421825-B1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-01-01 | — | — | EP | claimed |
| US-20130244997-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (US) | 2013-09-19 | — | — | US | claimed |
| US-8530593-B2 | Catalyst compounds and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-09-10 | — | — | US | claimed |
| WO-1993001715-A1 | 1,4-DIARYL-1-CYCLOPROPYL-4-SUBSTITUTED BUTANES AS INSECTICIDES AND ACARICIDES | FMC CORPORATION (US) | 1993-02-04 | — | — | WO | claimed |
| EP-0357610-B1 | INSECTICIDAL CYCLOPROPYL-SUBSTITUTED DI(ARYL) COMPOUNDS | FMC Corporation (US) | 1992-09-16 | — | — | EP | claimed |
| US-5118704-A | Treating disorders of central nervous, cardiovascular and endocrine systems | WHITBY RESEARCH, INC. (US) | 1992-06-02 | — | — | US | claimed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | claimed |
| EP-0357610-A1 | INSECTICIDAL CYCLOPROPYL-SUBSTITUTED DI(ARYL) COMPOUNDS. | FMC CORP (US) | 1990-03-14 | — | — | EP | claimed |
| US-4898863-A | Heterocyclic carboxamides | ICI AMERICAS INC. (US) | 1990-02-06 | — | — | US | claimed |
| US-4808762-A | Insecticidal cyclopropyl-substituted di(aryl) compounds | FMC CORPORATION (US) | 1989-02-28 | — | — | US | claimed |
| WO-1988008416-A1 | INSECTICIDAL CYCLOPROPYL-SUBSTITUTED DI(ARYL) COMPOUNDS | FMC CORPORATION (US) | 1988-11-03 | — | — | WO | claimed |
| EP-0269514-A2 | Derivatives of 2,2-dimethylcyclopropanecarboxylic acid bearing a saturated halogenated chain at C-3, process and intermediates for their preparation, their use as pesticides and compositions containing them | ROUSSEL-UCLAF (FR) | 1988-06-01 | — | — | EP | claimed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10076517-B2 | Methods and pharmaceutical compositions for the treatment of fibrosis | LIPA, MGLL, PNLIP | PDCD1 4839/4885CD274 4732/4885ALDH1A1 779/4885 |
| US-20130244997-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | PNLIP, LPL, LIPA | PDCD1 3933/4885CD274 4756/4885ALDH1A1 364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.