Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PAM | P19021 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126150 | 0.81 | MAPT (0.41) | MAPTLMNAKMT2AALDH1A1CYP1A2 | |
| SCHEMBL23126427 | 0.78 | KLK7 (0.41) | LMNAKMT2AALDH1A1POLBL3MBTL1 | |
| SCHEMBL9396561 | 0.75 | CYP1A2 (0.46) | MAPTPAMGLASMN1; SMN2KMT2A | |
| SCHEMBL15505363 | 0.74 | KMT2A (0.59) | KMT2A | |
| SCHEMBL18025027 | 0.72 | KMT2A (0.39) | MAPTHTTLMNAKMT2ATSHR | |
| SCHEMBL16328281 | 0.68 | POLB (0.50) | MAPTGAALMNAKMT2ACYP1A2 | |
| SCHEMBL21132827 | 0.67 | MAPT (0.40) | MAPTHTTGAASMN1; SMN2LMNA | |
| SCHEMBL24613075 | 0.66 | KMT2A (0.48) | KMT2A | |
| SCHEMBL23730549 | 0.64 | POLB (0.42) | MAPTHTTGAALMNAKMT2A | |
| SCHEMBL12401091 | 0.64 | ALDH1A1 (0.48) | MAPTHTTSMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190389911-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2019-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190389911-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | CACYBP, HSPBP1, PEBP1 | MAPT 4459/4885PAM 3662/4885HTT 3867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.