SCHEMBL4126150

SCHEMBL4126150

O=C(O)CNC(=O)COC1c2ccccc2-c2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41
CYP1A2 P05177 1/20 0.39
TSHR P16473 1/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.38
ITGB3 P05106 1/20 0.38
ITGB1 P05556 1/20 0.38
ITGAV P06756 1/20 0.38
ITGA5 P08648 1/20 0.38
PTPRC P08575 2/20 0.38
CTSL P07711 1/20 0.38
PTPN13 Q12923 1/20 0.38
KEAP1 Q14145 1/20 0.38
PTGIR P43119 1/20 0.37
ABAT P80404 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC8 Q9BY41 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9396561 0.82 CYP1A2 (0.46) MAPTCYP1A2TSHRKMT2APTGDR2
SCHEMBL21602876 0.81 MAPT (0.39) MAPTCYP1A2TSHRKMT2ALMNA
SCHEMBL18025027 0.78 KMT2A (0.39) MAPTTSHRKMT2ALMNAHDAC3
SCHEMBL17037312 0.78 KMT2A (0.43) MAPTCYP1A2TSHRKMT2APTGDR2
SCHEMBL18025028 0.78 IDO1 (0.50) MAPTTSHRKMT2ALMNAALDH1A1
SCHEMBL21895855 0.74 KMT2A (0.45) MAPTCYP1A2TSHRKMT2AITGB3
SCHEMBL16328281 0.74 POLB (0.50) MAPTCYP1A2TSHRKMT2ALMNA
SCHEMBL8410783 0.73 LMNA (0.64) MAPTCYP1A2KMT2ALMNAPTGDR2
SCHEMBL21132827 0.72 MAPT (0.40) MAPTTSHRKMT2ALMNAHDAC3
SCHEMBL9398200 0.72 HDAC3 (0.59) CYP1A2TSHRLMNAHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004099288-A1 POLYETHYLENEIMINE POLYMERS CARLSBERG A/S (DK) 2004-11-18 WO claimed
US-20090023606-A1 Beaded and Cross-Linked Poly(Aminoalkylene)Matrix and Uses Thereof VERSAMATRIX A/S (DK) 2009-01-22 US disclosed
EP-1778740-A1 BEADED AND CROSS-LINKED POLY(AMINOALKYLENE) MATRIX AND USES THEREOF VersaMatrix A/S (DK) 2007-05-02 EP disclosed
WO-2006015594-A1 BEADED AND CROSS-LINKED POLY(AMINOALKYLENE) MATRIX AND USES THEREOF VERSAMATRIX A/S (DK) 2006-02-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090023606-A1 Beaded and Cross-Linked Poly(Aminoalkylene)Matrix and Uses Thereof PLOD3, PLOD2, PCNA MAPT 3289/4885CYP1A2 1851/4885TSHR 4814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.