Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 5/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21602953 | 0.82 | FGFR4 (0.40) | FGFR4MEN1KMT2AKDM4EGRM5 | |
| SCHEMBL30450965 | 0.79 | MEN1 (0.47) | FGFR4MEN1KMT2AHTT | |
| SCHEMBL20330658 | 0.79 | MEN1 (0.47) | FGFR4MEN1KMT2AHTT | |
| SCHEMBL20330605 | 0.78 | MEN1 (0.38) | FGFR4L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL20330599 | 0.71 | MEN1 (0.38) | FGFR4MEN1KMT2AHTT | |
| SCHEMBL20330632 | 0.70 | ATM (0.38) | FGFR4ATMTDP1L3MBTL1MEN1 | |
| SCHEMBL30045129 | 0.70 | ATM (0.38) | FGFR4ATMTDP1L3MBTL1MEN1 | |
| SCHEMBL21251874 | 0.69 | FGFR4 (0.35) | FGFR4MEN1KMT2AHTTFGFR2 | |
| SCHEMBL21314920 | 0.66 | THRB (0.43) | MEN1KMT2A | |
| SCHEMBL674040 | 0.65 | ALDH1A1 (0.65) | ATMTDP1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019242587-A1 | HIGHLY SELECTIVE FGFR I INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2019-12-26 | — | — | WO | disclosed |