Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 4/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21603196 | 0.79 | CHRM4 (0.49) | CHRNB2CHRNA4 | |
| SCHEMBL26665387 | 0.78 | LIPE (0.49) | LIPESCN9ACHRNB2CHRNA4AXL | |
| SCHEMBL29202321 | 0.77 | LIPE (0.55) | LIPEPIK3CDPIK3CALPLLIPG | |
| SCHEMBL23207692 | 0.74 | LIPE (0.47) | LIPESCN9ACHRNB2CHRNA4AXL | |
| SCHEMBL21607026 | 0.74 | HRH1 (0.47) | LIPEPIK3CASCN9ACHRNB2CHRNA4 | |
| SCHEMBL23207693 | 0.74 | LIPE (0.47) | LIPESCN9ACHRNB2CHRNA4AXL | |
| SCHEMBL29277434 | 0.74 | LIPE (0.47) | LIPEPIK3CDPIK3CASCN9ACHRNB2 | |
| SCHEMBL26709805 | 0.74 | CHRNB2 (0.46) | LIPESCN9ACHRNB2CHRNA4AXL | |
| Hydrochloric Acid SCHEMBL23168140 | 0.73 | LIPE (0.46) | LIPESCN9ACHRNB2CHRNA4AXL | |
| Hydrochloric Acid SCHEMBL23168136 | 0.73 | LIPE (0.46) | LIPESCN9ACHRNB2CHRNA4AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243527-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |