Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29202321 | 0.86 | LIPE (0.55) | LIPESCN9ACHRNB2CHRNA4ACACB | |
| SCHEMBL31307974 | 0.84 | LIPE (0.44) | LIPESCN9ACHRNB2CHRNA4SCN10A | |
| SCHEMBL28612117 | 0.81 | GRIN1 (0.46) | CHRNB2CHRNA4 | |
| SCHEMBL29277440 | 0.78 | TEAD1 (0.46) | LIPEACACB | |
| SCHEMBL31308062 | 0.77 | KDM1A (0.39) | ACACBCHRNA7 | |
| SCHEMBL26665387 | 0.76 | LIPE (0.49) | LIPESCN9ACHRNB2CHRNA4TRPV4 | |
| SCHEMBL29277452 | 0.76 | HCRTR2 (0.40) | ACACB | |
| SCHEMBL26709805 | 0.75 | CHRNB2 (0.46) | LIPESCN9ACHRNB2CHRNA4TRPV4 | |
| SCHEMBL21603313 | 0.74 | LIPE (0.48) | LIPESCN9ACHRNB2CHRNA4ACACB | |
| SCHEMBL29277439 | 0.74 | ACACB (0.39) | ACACBAXLTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |