Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095111 | 0.75 | KEAP1 (0.46) | MAPTALDH1A1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL10836830 | 0.74 | POLB (0.50) | ALDH1A1ASAH1ACER2SMN1; SMN2CYP1A2 | |
| SCHEMBL9517922 | 0.74 | KEAP1 (0.45) | MAPTALDH1A1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL10728992 | 0.72 | ALDH1A1 (0.50) | MAPTALDH1A1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL9858681 | 0.72 | KDM4E (0.43) | MAPTSMN1; SMN2CYP1A2CYP2D6TSHR | |
| SCHEMBL10732000 | 0.71 | ALDH1A1 (0.46) | MAPTALDH1A1SMN1; SMN2TSHRPOLB | |
| SCHEMBL22922972 | 0.71 | EPHX2 (0.43) | ALDH1A1TSHRCYP2C19POLB | |
| SCHEMBL29979370 | 0.71 | EPHX2 (0.43) | ALDH1A1TSHRCYP2C19POLB | |
| SCHEMBL28457741 | 0.71 | ALDH1A1 (0.33) | MAPTALDH1A1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL1723688 | 0.71 | KEAP1 (0.33) | MAPTALDH1A1SMN1; SMN2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243580-A1 | PHENYLPHOSPHINO COMPOUNDS AS PROCESS STABILIZERS | CLARIANT PLASTICS & COATINGS LTD (CH) | 2019-12-26 | — | — | WO | disclosed |