Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311300 | 0.80 | HDAC1 (0.66) | CYP19A1HDAC1HSP90AB1HRH4GLS | |
| SCHEMBL22499185 | 0.77 | TDP1 (0.58) | ALDH1A1 | |
| SCHEMBL15796691 | 0.76 | HDAC1 (0.53) | CYP19A1HDAC1HSP90AB1HRH4GLS | |
| SCHEMBL5052830 | 0.75 | HDAC1 (0.70) | CYP19A1HDAC1HSP90AB1HRH4 | |
| Acetic Acid SCHEMBL28328685 | 0.75 | CYP19A1 (0.86) | CYP19A1HDAC1HSP90AB1HRH4ALDH1A1 | |
| SCHEMBL21606709 | 0.74 | HSD11B1 (0.61) | HDAC1 | |
| SCHEMBL24666587 | 0.74 | CYP19A1 (0.57) | CYP19A1HDAC1HSP90AB1HRH4ALDH1A1 | |
| SCHEMBL15796670 | 0.74 | HDAC1 (0.77) | CYP19A1HDAC1 | |
| SCHEMBL15796690 | 0.73 | HDAC1 (0.55) | CYP19A1HDAC1HSP90AB1HRH4GLS | |
| SCHEMBL22958941 | 0.73 | HDAC1 (0.65) | CYP19A1HDAC1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284668-A1 | GOLD (I)-PHOSPHINE 1,2,3-TRIAZOLE DERIVATIVES WITH ANTIBIOTIC PROPERTIES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-09-16 | — | — | US | disclosed |
| WO-2019243273-A1 | GOLD (I)-PHOSPHINE 1,2,3-TRIAZOLE DERIVATIVES WITH ANTIOBIOTIC PROPERTIES | UNIVERSITÉ DE STRASBOURG (FR) | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284668-A1 | GOLD (I)-PHOSPHINE 1,2,3-TRIAZOLE DERIVATIVES WITH ANTIBIOTIC PROPERTIES | PADI3, PADI1, PADI4 | CYP19A1 3583/4885HDAC1 1564/4885HSP90AB1 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.