Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PTGFR | P43088 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30205123 | 1.00 | TDP1 (0.42) | TDP1L3MBTL1MAPK1MEN1ABL1 | |
| SCHEMBL30331593 | 1.00 | TDP1 (0.42) | TDP1L3MBTL1MAPK1MEN1ABL1 | |
| SCHEMBL23812201 | 0.93 | TDP1 (0.47) | TDP1L3MBTL1MAPK1MEN1ABL1 | |
| SCHEMBL16478559 | 0.93 | TDP1 (0.47) | TDP1L3MBTL1MAPK1MEN1ABL1 | |
| SCHEMBL16141184 | 0.90 | HLCS (0.39) | TDP1MEN1KMT2AKEAP1CA12 | |
| SCHEMBL30929050 | 0.84 | HSP90AB1 (0.43) | PKMKEAP1 | |
| SCHEMBL30929049 | 0.84 | HSP90AB1 (0.43) | PKMKEAP1 | |
| SCHEMBL9971307 | 0.83 | KEAP1 (0.40) | TDP1KEAP1ALDH1A1 | |
| SCHEMBL30205084 | 0.82 | KEAP1 (0.40) | TDP1KEAP1ALDH1A1 | |
| SCHEMBL21606770 | 0.78 | CYP2J2 (0.32) | TDP1L3MBTL1MAPK1MEN1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243273-A1 | GOLD (I)-PHOSPHINE 1,2,3-TRIAZOLE DERIVATIVES WITH ANTIOBIOTIC PROPERTIES | UNIVERSITÉ DE STRASBOURG (FR) | 2019-12-26 | — | — | WO | disclosed |