Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079969 | 0.84 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL479043 | 0.79 | PDE4B (0.36) | LMNAALDH1A1KDM4E | |
| SCHEMBL21607820 | 0.73 | LMNA (0.33) | LMNAGAAKDM4E | |
| SCHEMBL10715626 | 0.73 | KDM1A (0.37) | ALDH1A1GAAKDM4E | |
| SCHEMBL22978627 | 0.73 | BCHE (0.30) | — | |
| SCHEMBL21607865 | 0.73 | NOTUM (0.37) | ALDH1A1 | |
| SCHEMBL24510005 | 0.73 | KDM4E (0.33) | ALDH1A1KDM4E | |
| SCHEMBL9058610 | 0.73 | ALDH1A1 (0.37) | LMNAALDH1A1GAAKDM4E | |
| SCHEMBL13373633 | 0.72 | HTR2A (0.50) | LMNAALDH1A1GAAKDM4E | |
| SCHEMBL22978634 | 0.72 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300900-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-09-30 | — | — | US | disclosed |
| WO-2019243531-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300900-A1 | OGA INHIBITOR COMPOUNDS | OGA, OGT, GRN | LMNA 848/4885ALDH1A1 3839/4885GAA 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.