Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24510005 | 0.81 | KDM4E (0.33) | — | |
| SCHEMBL21607865 | 0.81 | NOTUM (0.37) | BCHE | |
| SCHEMBL26970966 | 0.81 | BCHE (0.32) | BCHE | |
| SCHEMBL21597038 | 0.79 | ATM (0.36) | BCHE | |
| SCHEMBL10715626 | 0.75 | KDM1A (0.37) | — | |
| SCHEMBL22978634 | 0.73 | ALDH1A1 (0.31) | — | |
| SCHEMBL24685885 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL21607979 | 0.73 | LMNA (0.35) | — | |
| SCHEMBL25786587 | 0.71 | BCHE (0.33) | BCHE | |
| SCHEMBL1279668 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010334-A1 | HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS | Novartis AG (CH) | 2022-06-15 | — | — | EP | disclosed |
| WO-2021026672-A1 | HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS | NOVARTIS AG (CH) | 2021-02-18 | — | — | WO | disclosed |
| WO-2021028806-A1 | HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS | NOVARTIS AG (CH) | 2021-02-18 | — | — | WO | disclosed |