Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NQO1 | P15559 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10715626 | 0.78 | KDM1A (0.37) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL24685885 | 0.76 | ALDH1A1 (0.33) | ALDH1A1MAPTMEN1KMT2ANQO1 | |
| SCHEMBL22978627 | 0.73 | BCHE (0.30) | — | |
| SCHEMBL24510005 | 0.73 | KDM4E (0.33) | ALDH1A1MAPTKMT2A | |
| SCHEMBL21607865 | 0.73 | NOTUM (0.37) | ALDH1A1MEN1KMT2A | |
| SCHEMBL21607979 | 0.72 | LMNA (0.35) | ALDH1A1 | |
| SCHEMBL4753817 | 0.72 | ALDH1A1 (0.54) | ALDH1A1KMT2A | |
| SCHEMBL21597038 | 0.71 | ATM (0.36) | ALDH1A1 | |
| SCHEMBL23854653 | 0.71 | MEN1 (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL21607903 | 0.68 | KMT2A (0.48) | ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026672-A1 | HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS | NOVARTIS AG (CH) | 2021-02-18 | — | — | WO | disclosed |