Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.31 |
| ▸ | MYLK | Q15746 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27942728 | 0.82 | BCHE (0.38) | BCHENOTUMCA1CA2CA9 | |
| SCHEMBL3508715 | 0.79 | BCHE (0.36) | BCHE | |
| SCHEMBL25290933 | 0.77 | DUT (0.30) | — | |
| SCHEMBL28400800 | 0.76 | P2RX7 (0.42) | CA1CA2CA9 | |
| SCHEMBL8270922 | 0.75 | FFAR1 (0.40) | RIPK1 | |
| SCHEMBL14012143 | 0.74 | BCHE (0.33) | BCHE | |
| SCHEMBL18436578 | 0.73 | RIPK1 (0.34) | RIPK1 | |
| SCHEMBL479082 | 0.73 | CXCR2 (0.39) | BCHECA1CA2CA9 | |
| SCHEMBL32667294 | 0.73 | RIPK1 (0.34) | RIPK1 | |
| SCHEMBL22435182 | 0.73 | GPR84 (0.35) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300900-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-09-30 | — | — | US | disclosed |
| WO-2019243531-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300900-A1 | OGA INHIBITOR COMPOUNDS | OGA, OGT, GRN | RIPK1 2104/4885BCHE 76/4885PRKCE 3057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.