Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21598726 | 1.00 | MAPK1 (0.37) | MAPK1KDM4EPOLBKMT2ALMNA | |
| SCHEMBL21608245 | 1.00 | MAPK1 (0.37) | MAPK1KDM4EPOLBKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL30254052 | 0.98 | MAPK1 (0.36) | MAPK1KDM4EPOLBKMT2ALMNA | |
| SCHEMBL34468424 | 0.81 | SMN1; SMN2 (0.43) | MAPK1KDM4EKMT2ALMNASMN1; SMN2 | |
| SCHEMBL21598694 | 0.79 | S1PR1 (0.39) | MAPK1POLBKMT2AMEN1MALT1 | |
| SCHEMBL17512693 | 0.78 | MAPK1 (0.36) | MAPK1KDM4EPOLBKMT2ALMNA | |
| SCHEMBL28550715 | 0.74 | MAPK1 (0.38) | MAPK1KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL16654737 | 0.74 | L3MBTL1 (0.35) | MAPK1KDM4EPOLBKMT2ALMNA | |
| SCHEMBL21598682 | 0.70 | RORC (0.47) | MAPK1KMT2ALMNASMN1; SMN2MALT1 | |
| SCHEMBL115753 | 0.69 | TSHR (0.41) | MAPK1KDM4EPOLBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10888550-B2 | Pyrazole derivatives as MALT1 inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2021-01-12 | — | — | US | disclosed |
| WO-2019243965-A1 | PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10888550-B2 | Pyrazole derivatives as MALT1 inhibitors | MALT1, PPP3R1, SQSTM1 | MAPK1 386/4885KDM4E 3396/4885POLB 4389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.