SCHEMBL21609237

SCHEMBL21609237

COc1cccc(OC)c1SNc1noc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 1/20 0.46
TP53 P04637 3/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
HIF1A Q16665 2/20 0.45
MAPT P10636 2/20 0.45
EPHX2 P34913 9/20 0.44
KCNA5 P22460 2/20 0.43
MAOA P21397 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21609162 0.80 KCNA5 (0.43) KAT6AHIF1AMAPTKCNA5
SCHEMBL21609030 0.78 SMN1; SMN2 (0.49) KAT6ATP53SMN1; SMN2HIF1AMAPT
SCHEMBL21609065 0.76 KCNA5 (0.47) KAT6ATP53SMN1; SMN2KCNA5
SCHEMBL21609078 0.76 KAT6A (0.42) KAT6AKCNA5
SCHEMBL21609154 0.76 EPHX2 (0.49) KAT6ATP53SMN1; SMN2HIF1AMAPT
SCHEMBL22817445 0.76 KAT6A (0.41) KAT6AKCNA5
SCHEMBL21609193 0.75 ALDH1A1 (0.43) MAPTKCNA5
SCHEMBL22817396 0.74 NPC1 (0.34) KAT6ATP53SMN1; SMN2MAPTMAOA
SCHEMBL21609246 0.73 KAT6A (0.64) KAT6A
SCHEMBL26801430 0.72 KAT7 (0.68) KAT6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019243491-A1 COMPOUNDS CTXT PTY LIMITED (AU) 2019-12-26 WO disclosed