SCHEMBL21609231

SCHEMBL21609231

Cc1cnc2c(S(=O)(=O)Nc3noc4cccc(Cl)c34)cccc2c1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC40A1 Q9NP59 7/20 0.51
ATM Q13315 1/20 0.45
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SLC16A3 O15427 1/20 0.42
BRD4 O60885 2/20 0.41
CCR4 P51679 4/20 0.40
EDNRB P24530 1/20 0.39
EDNRA P25101 1/20 0.39
KAT6A Q92794 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29652464 0.86 KAT6A (0.47) KAT6A
SCHEMBL21641914 0.86 KAT6A (0.47) KAT6A
SCHEMBL21609115 0.84 MEN1 (0.55) SLC40A1ATMMEN1KMT2A
SCHEMBL21609121 0.78 EDNRA (0.50) BRD4CCR4EDNRBEDNRAKAT6A
SCHEMBL21609081 0.78 CCKBR (0.42) SLC40A1MEN1KMT2ABRD4CCR4
SCHEMBL21609018 0.76 KMT2A (0.52) MEN1KMT2A
SCHEMBL21609022 0.76 HTR2A (0.44) BRD4EDNRBEDNRA
SCHEMBL21609028 0.76 BRD4 (0.41) SLC40A1MEN1KMT2ABRD4CCR4
SCHEMBL21609217 0.76 EDNRB (0.46) SLC40A1MEN1KMT2AEDNRBEDNRA
SCHEMBL29652497 0.76 EDNRB (0.46) SLC40A1MEN1KMT2AEDNRBEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3810602-B1 COMPOUNDS CTXT PTY LTD (AU) 2023-11-01 EP disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 US disclosed
US-20200039945-A1 Compounds CTXT PTY LIMITED (AU) 2020-02-06 US disclosed
WO-2019243491-A1 COMPOUNDS CTXT PTY LIMITED (AU) 2019-12-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 SLC40A1 459/4885ATM 3790/4885MEN1 122/4885
US-20200039945-A1 Compounds SLC10A1, ABCB11, PCSK9 SLC40A1 460/4885ATM 3790/4885MEN1 121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.