Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Acrylamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 known ✓ | P22455 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL16402988 | 1.00 | ALDH1A1 (0.73) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL29092492 | 1.00 | ALDH1A1 (0.73) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL28918491 | 1.00 | ALDH1A1 (0.73) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL3255310 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL28734833 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL27770486 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL28807078 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL5807989 | 0.90 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL27291386 | 0.89 | ALDH1A1 (0.58) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL7754556 | 0.88 | ALDH1A1 (0.65) | ALDH1A1TSHRFGFR4LMNACA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181261-B | Hyperbranched hydrophilizing agent, hydrophilically modified resin and preparation method thereof | 中化石化销售有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-115537272-A | Monocrystalline silicon sample wafer cleaning agent and cleaning method | 新疆晶科能源有限公司 | 2022-12-30 | — | — | CN | claimed |
| CN-115181261-A | Hyperbranched hydrophilic agent, hydrophilic modified resin and preparation method thereof | 中化石化销售有限公司 | 2022-10-14 | — | — | CN | claimed |
| CN-112745464-A | Phosphate-containing high-adaptability early-strength polycarboxylate superplasticizer and preparation method and application thereof | 广州市建筑科学研究院有限公司 | 2021-05-04 | — | — | CN | claimed |
| CN-111732885-B | Waterborne elastic polyurethane flame-retardant coating and preparation method thereof | 广东顺德德图新材料有限公司 | 2020-12-29 | — | — | CN | claimed |
| CN-111978623-A | Preparation method of winding film and winding film prepared by preparation method | 成都友一包装材料有限公司 | 2020-11-24 | — | — | CN | claimed |
| CN-111732885-A | Waterborne elastic polyurethane flame-retardant coating and preparation method thereof | 广东顺德德图新材料有限公司 | 2020-10-02 | — | — | CN | claimed |
| CN-210786669-U | Environmental protection device that polyacrylamide phosphoric acid solution washing sprayed | 湖北都兴隆农业技术有限公司 | 2020-06-19 | — | — | CN | claimed |
| CN-106752411-B | A kind of automobile-used volatilization prevention material of wholesale business petroleum transportation and preparation method thereof | 哈尔滨理工大学 | 2019-11-08 | — | — | CN | claimed |
| CN-107001641-A | Polymethacrylimide acid polymer and preparation and the method used | 陶氏环球技术有限责任公司 | 2017-08-01 | — | — | CN | claimed |
| CN-106751796-A | A kind of composite material and preparation method thereof | 天津映之科技有限公司 | 2017-05-31 | — | — | CN | claimed |
| CN-106752411-A | A kind of automobile-used volatilization prevention material of wholesale business petroleum transportation and preparation method thereof | 天津诚信科技发展股份有限公司 | 2017-05-31 | — | — | CN | claimed |
| CN-106609065-A | Volatilization-preventing material for wholesale business transportation vehicle, and preparation method thereof | 天津诚信科技发展股份有限公司 | 2017-05-03 | — | — | CN | claimed |
| CN-106589737-A | Novel macromolecular composite material and preparation method thereof | 天津盼易科技有限公司 | 2017-04-26 | — | — | CN | claimed |
| CN-114848503-B | Dental materials based on polymerizable thiourea derivatives | 义获嘉伟瓦登特公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-118161520-A | Lipolytic composition using surface-modified gas-generating nanoparticles | 超新星生物有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-113880985-B | Composite material with reduced polymeric shrinkage stress | 义获嘉伟瓦登特公司 | 2024-05-17 | — | — | CN | disclosed |
| EP-0688360-A1 | BONE STIMULATING FACTOR | OSTEOPHARM LIMITED (CA) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994020615-A1 | BONE STIMULATING FACTOR | OSTEOPHARM LIMITED (CA) | 1994-09-15 | — | — | WO | disclosed |
| US-4705545-A | Thin film polymer blend membranes | UOP INC. (US) | 1987-11-10 | — | — | US | disclosed |