Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Acrylamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 known ✓ | P22455 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL16402988 | 0.97 | ALDH1A1 (0.73) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL28918491 | 0.97 | ALDH1A1 (0.73) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL2160931 | 0.97 | ALDH1A1 (0.73) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL29092492 | 0.97 | ALDH1A1 (0.73) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL28734833 | 0.94 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL3255310 | 0.94 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL28807078 | 0.94 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL5807989 | 0.88 | ALDH1A1 (0.69) | ALDH1A1TSHRFGFR4LMNACA4 | |
| Acrylamide SCHEMBL17627782 | 0.87 | — | — | |
| Acrylamide SCHEMBL27291386 | 0.86 | ALDH1A1 (0.58) | ALDH1A1TSHRFGFR4LMNACA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101492562-B | Polyacrylamide/calcium phosphate nano-composite material and microwave auxiliary liquid phase preparation method thereof | SHANGHAI INSTITUTE OF CERAMICS, CHINESE ACADEMY OF SCIENCES (CN) | 2011-12-14 | — | — | CN | disclosed |
| CN-101492562-A | Polyacrylamide/calcium phosphate nano-composite material and microwave auxiliary liquid phase preparation method thereof | SHANGHAI INST SILICATE CAS (CN) | 2009-07-29 | — | — | CN | disclosed |