Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21609606 | 0.69 | NPSR1 (0.41) | LMNANPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL29477252 | 0.68 | LMNA (1.00) | LMNANPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL6589568 | 0.65 | MAPT (0.54) | LMNANPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL6417214 | 0.65 | KDM4E (0.60) | LMNANPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL576260 | 0.62 | MEN1 (0.48) | LMNANPSR1HTTMAPTHPGD | |
| SCHEMBL5647444 | 0.62 | NR1H2 (0.52) | LMNASMN1; SMN2HTTMAPTHSD17B10 | |
| SCHEMBL28693353 | 0.62 | USP2 (0.58) | NPC1RAB9AMAPTHSD17B10MEN1 | |
| SCHEMBL9013731 | 0.62 | NPC1 (0.47) | LMNANPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL3906125 | 0.62 | GAA (0.47) | LMNAHSD17B10KDM4EGAAATM | |
| SCHEMBL3267043 | 0.62 | MPO (0.46) | NPC1RAB9AMAPTHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810588-A1 | SUBSTITUTED 4-HETEROARYLOXYPYRIDINES AND SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS | Bayer Aktiengesellschaft (DE) | 2021-04-28 | — | — | EP | disclosed |
| CN-112384507-A | Substituted 4-heteroaryloxypyridines and their salts and their use as herbicides | 拜耳公司 | 2021-02-19 | — | — | CN | disclosed |
| WO-2020002085-A1 | SUBSTITUTED 4-HETEROARYLOXYPYRIDINES AND SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-01-02 | — | — | WO | disclosed |