Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 2/20 | 0.49 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.49 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21614713 | 0.79 | GAA (0.44) | SMARCA2SMARCA4PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL21614711 | 0.78 | RAB9A (0.45) | PRKAG1PRKAA2PRKAA1PRKAB1CACNA1G | |
| SCHEMBL21611974 | 0.73 | PRKAG1 (0.46) | SMARCA2SMARCA4PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL22125283 | 0.73 | SMARCA2 (0.60) | SMARCA2SMARCA4MALT1HDAC4HDAC6 | |
| SCHEMBL6524094 | 0.72 | MAPT (0.53) | DGAT1MAPTMEN1LMNAKMT2A | |
| SCHEMBL21614710 | 0.70 | GAA (0.44) | PRKAG1PRKAA2PRKAA1PRKAB1CACNA1G | |
| SCHEMBL21614712 | 0.70 | CACNA1G (0.40) | PRKAG1PRKAA2PRKAA1PRKAB1CACNA1G | |
| SCHEMBL30763499 | 0.70 | CACNA1G (0.40) | PRKAG1PRKAA2PRKAA1PRKAB1CACNA1G | |
| SCHEMBL21611922 | 0.69 | SMARCA2 (0.49) | SMARCA2SMARCA4MAPTLMNAMALT1 | |
| SCHEMBL21611928 | 0.69 | MAPT (0.50) | SMARCA2SMARCA4MAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818045-A1 | PQSR INVERSE AGONISTS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2021-05-12 | — | — | EP | disclosed |
| WO-2020007938-A1 | PqsR INVERSE AGONISTS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2020-01-09 | — | — | WO | disclosed |