Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | EBP | Q15125 | 2/20 | 0.33 |
| ▸ | DHCR7 | Q9UBM7 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21613808 | 0.86 | DHCR7 (0.39) | KDM4EKMT2AMEN1EBPDHCR7 | |
| SCHEMBL21613703 | 0.76 | KDM4E (0.41) | ALDH1A1KDM4EKMT2AMEN1EBP | |
| SCHEMBL22080872 | 0.75 | KDM4E (0.37) | ALDH1A1KDM4EKMT2AEBPDHCR7 | |
| SCHEMBL22081626 | 0.74 | KDM4E (0.38) | ALDH1A1KDM4EKMT2AMEN1EBP | |
| SCHEMBL21613709 | 0.74 | CHRNA7 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL22081202 | 0.74 | HTT (0.39) | ALDH1A1KDM4EKMT2AMEN1EBP | |
| SCHEMBL21613735 | 0.74 | ACHE (0.45) | ALDH1A1KDM4EKMT2AMEN1EBP | |
| SCHEMBL21613752 | 0.74 | KDM4E (0.41) | ALDH1A1KDM4EKMT2AMEN1EBP | |
| SCHEMBL17007475 | 0.72 | DHCR7 (0.50) | ALDH1A1KMT2AMEN1EBPDHCR7 | |
| SCHEMBL21613791 | 0.72 | LMNA (0.41) | ALDH1A1KDM4EKMT2AMEN1EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3044218-B1 | THERAPEUTICS TARGETING TRUNCATED ADENOMATOUS POLYPOSIS COLI (APC) PROTEINS | UNIV TEXAS (US) | 2020-05-27 | — | — | EP | disclosed |