Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NT5E | P21589 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24695428 | 0.85 | AHCY (0.50) | AHCYHIF1ATP53ADORA3ADORA2A | |
| SCHEMBL15643110 | 0.85 | AHCY (0.50) | AHCYHIF1ATP53ADORA3ADORA2A | |
| SCHEMBL21614180 | 0.82 | NT5E (0.52) | AHCYLMNANT5EHIF1ACA5A | |
| SCHEMBL25396825 | 0.82 | AHCY (0.55) | AHCYLMNANT5EHIF1ACA5A | |
| SCHEMBL15643129 | 0.81 | ADORA3 (0.50) | NT5EPNPPDE3AADORA3 | |
| SCHEMBL20670946 | 0.81 | AHCY (0.54) | AHCYLMNANT5EHIF1ACA5A | |
| SCHEMBL21614181 | 0.81 | AHCY (0.54) | AHCYLMNANT5EHIF1ACA5A | |
| SCHEMBL24195283 | 0.81 | AHCY (0.54) | AHCYLMNANT5EHIF1ACA5A | |
| SCHEMBL31652941 | 0.81 | AHCY (0.54) | AHCYLMNANT5EHIF1ACA5A | |
| SCHEMBL30689530 | 0.81 | AHCY (0.54) | AHCYLMNANT5EHIF1ACA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151048-A1 | CRYSTAL FORM, PREPARATION METHOD, AND APPLICATION OF 4′-SUBSTITUTED NUCLEOSIDE | HENAN GENUINE BIOTECH CO., LTD. (CN) | 2023-05-18 | — | — | US | disclosed |
| WO-2020007070-A1 | CRYSTAL FORM, PREPARATION METHOD, AND APPLICATION OF 4'-SUBSTITUTED NUCLEOSIDE | 河南真实生物科技有限公司 | 2020-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151048-A1 | CRYSTAL FORM, PREPARATION METHOD, AND APPLICATION OF 4′-SUBSTITUTED NUCLEOSIDE | PNP, CCR5, CD4 | AHCY 1327/4885LMNA 2268/4885NT5E 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.