Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.54 |
| ▸ | NQO2 | P16083 | 3/20 | 0.54 |
| ▸ | SPR | P35270 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21614208 | 0.91 | CDK2 (0.48) | MTNR1AMTNR1BNQO2SPRCDK2 | |
| SCHEMBL6577287 | 0.88 | NQO2 (0.47) | MTNR1AMTNR1BNQO2SPRCDK2 | |
| SCHEMBL21614215 | 0.87 | SNCA (0.53) | MTNR1AMTNR1BNQO2SPRCDK2 | |
| SCHEMBL21614209 | 0.87 | MTNR1A (0.53) | MTNR1AMTNR1BNQO2SPRCDK2 | |
| SCHEMBL29657293 | 0.87 | NQO2 (0.53) | MTNR1AMTNR1BNQO2SPRCDK2 | |
| SCHEMBL24453122 | 0.87 | NQO2 (0.53) | MTNR1AMTNR1BNQO2SPRCDK2 | |
| SCHEMBL21614211 | 0.86 | MTNR1A (0.73) | MTNR1AMTNR1BNQO2SPRMEN1 | |
| SCHEMBL21614242 | 0.85 | NQO2 (0.51) | MTNR1AMTNR1BNQO2SPRMEN1 | |
| SCHEMBL21614223 | 0.84 | NR4A2 (0.51) | MTNR1AMTNR1BNQO2SPRCDK2 | |
| SCHEMBL14550631 | 0.84 | KMT2A (0.53) | MTNR1AMTNR1BNQO2TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162219-A1 | Chiral Bisamino-Ether Compounds, And Method of Preparation and Use Thereof | UNIV JINAN (CN) | 2022-05-26 | — | — | US | disclosed |
| WO-2020007017-A1 | CHIRAL BISAMINO-ETHER COMPOUNDS, AND METHOD OF PREPARATION AND USE THEREOF | JINAN UNIVERSITY (CN) | 2020-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162219-A1 | Chiral Bisamino-Ether Compounds, And Method of Preparation and Use Thereof | FHIT, BCAT1, BCAT2 | MTNR1A 4243/4885MTNR1B 4337/4885NQO2 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.