Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 13/20 | 0.66 |
| ▸ | BRAF | P15056 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21611777 | 0.88 | GPR142 (0.66) | GPR142BRAF | |
| SCHEMBL29084551 | 0.81 | CYP19A1 (0.53) | GPR142BRAFALDH1A1 | |
| SCHEMBL29625998 | 0.81 | CYP19A1 (0.53) | GPR142BRAFALDH1A1 | |
| SCHEMBL21615099 | 0.80 | GPR142 (1.00) | GPR142BRAF | |
| SCHEMBL21615098 | 0.79 | GPR142 (1.00) | GPR142BRAF | |
| SCHEMBL21615154 | 0.77 | GPR142 (1.00) | GPR142BRAF | |
| SCHEMBL4037558 | 0.76 | GPR142 (0.57) | GPR142BRAF | |
| SCHEMBL1404644 | 0.75 | KDM4E (0.47) | GPR142ALDH1A1 | |
| SCHEMBL21615090 | 0.75 | GPR142 (1.00) | GPR142 | |
| SCHEMBL4017487 | 0.72 | MMP2 (0.48) | GPR142 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3817811-B1 | TRIAZOLE BENZAMIDE DERIVATIVES AS GPR142 AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2024-04-03 | — | — | EP | disclosed |
| CN-112368049-B | Triazole benzamide derivatives as GPR142 agonists | 勃林格殷格翰国际有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-11179371-B2 | Triazole benzamide derivatives as GPR142 agonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-11-23 | — | — | US | disclosed |
| CN-112368049-A | Triazole benzamide derivatives as GPR142 agonists | 勃林格殷格翰国际有限公司 | 2021-02-12 | — | — | CN | disclosed |
| WO-2020007729-A1 | TRIAZOLE BENZAMIDE DERIVATIVES AS GPR142 AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11179371-B2 | Triazole benzamide derivatives as GPR142 agonists | GPR119, GPR142, GPR65 | GPR142 2/4885BRAF 3861/4885ALDH1A1 1991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.