Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Palmitic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | PPARD | Q03181 | 7/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Myristic Acid SCHEMBL2160003 | 1.00 | FFAR4 (0.40) | FFAR4FFAR1GPR84PPARGPPARD | |
| Stearic Acid SCHEMBL2160333 | 1.00 | FFAR4 (0.40) | FFAR4FFAR1GPR84PPARGPPARD | |
| Dodecanoate SCHEMBL14632965 | 1.00 | FFAR4 (0.40) | FFAR4FFAR1GPR84PPARGPPARD | |
| Oleic Acid SCHEMBL2161441 | 0.94 | PPARG (0.47) | FFAR4FFAR1PPARGPPARDPPARA | |
| Palmitic Acid SCHEMBL20786789 | 0.88 | GPR84 (0.52) | FFAR4FFAR1GPR84PPARGPPARD | |
| Glycinebetaine SCHEMBL2132643 | 0.86 | GPR84 (0.41) | FFAR1GPR84PPARDTSHRMAPT | |
| Glycinebetaine SCHEMBL3889766 | 0.86 | GPR84 (0.41) | FFAR1GPR84PPARDTSHRMAPT | |
| Glycinebetaine SCHEMBL2133338 | 0.86 | GPR84 (0.41) | FFAR1GPR84PPARDTSHRMAPT | |
| Glycinebetaine SCHEMBL2135218 | 0.86 | GPR84 (0.41) | FFAR1GPR84PPARDTSHRMAPT | |
| Glycinebetaine SCHEMBL2131138 | 0.86 | GPR84 (0.41) | FFAR1GPR84PPARDTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130023591-A1 | Phenyl-Containing Organopolysiloxane Composition, Raw Cosmetic Material, and Glossy Cosmetic Material | DOW CORNING TORAY CO., LTD. (JP) | 2013-01-24 | — | — | US | disclosed |
| EP-2519587-A1 | PHENYL-CONTAINING ORGANOPOLYSILOXANE COMPOSITION, RAW COSMETIC MATERIAL, AND GLOSSY COSMETIC MATERIAL | Dow Corning Toray Co., Ltd. (JP) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011081218-A1 | PHENYL-CONTAINING ORGANOPOLYSILOXANE COMPOSITION, RAW COSMETIC MATERIAL, AND GLOSSY COSMETIC MATERIAL | DOW CORNING TORAY CO., LTD. (JP) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023591-A1 | Phenyl-Containing Organopolysiloxane Composition, Raw Cosmetic Material, and Glossy Cosmetic Material | MITF, XPA, FANCI | FFAR4 2605/4885FFAR1 1413/4885GPR84 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.