Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | F7 | P08709 | 5/20 | 0.47 |
| ▸ | F3 | P13726 | 5/20 | 0.47 |
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | FABP4 | P15090 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitic Acid SCHEMBL2161701 | 0.94 | FFAR4 (0.40) | PPARGPPARDPPARAPTPN1HSD17B10 | |
| Dodecanoate SCHEMBL14632965 | 0.94 | FFAR4 (0.40) | PPARGPPARDPPARAPTPN1HSD17B10 | |
| Stearic Acid SCHEMBL2160333 | 0.94 | FFAR4 (0.40) | PPARGPPARDPPARAPTPN1HSD17B10 | |
| Myristic Acid SCHEMBL2160003 | 0.94 | FFAR4 (0.40) | PPARGPPARDPPARAPTPN1HSD17B10 | |
| Glycinebetaine SCHEMBL2131980 | 0.88 | FABP3 (0.46) | PPARGPPARDPPARAF7F3 | |
| Palmitic Acid SCHEMBL20786789 | 0.82 | GPR84 (0.52) | PPARGPPARDPPARAPTPN1HSD17B10 | |
| Oleic Acid SCHEMBL3250070 | 0.82 | PPARG (0.70) | PPARGPPARDPPARAF7F3 | |
| Glycinebetaine SCHEMBL2135218 | 0.81 | GPR84 (0.41) | PPARDMAPTNPSR1FFAR1TSHR | |
| Glycinebetaine SCHEMBL2133338 | 0.81 | GPR84 (0.41) | PPARDMAPTNPSR1FFAR1TSHR | |
| Glycinebetaine SCHEMBL2131138 | 0.81 | GPR84 (0.41) | PPARDMAPTNPSR1FFAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130023591-A1 | Phenyl-Containing Organopolysiloxane Composition, Raw Cosmetic Material, and Glossy Cosmetic Material | DOW CORNING TORAY CO., LTD. (JP) | 2013-01-24 | — | — | US | disclosed |
| EP-2519587-A1 | PHENYL-CONTAINING ORGANOPOLYSILOXANE COMPOSITION, RAW COSMETIC MATERIAL, AND GLOSSY COSMETIC MATERIAL | Dow Corning Toray Co., Ltd. (JP) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011081218-A1 | PHENYL-CONTAINING ORGANOPOLYSILOXANE COMPOSITION, RAW COSMETIC MATERIAL, AND GLOSSY COSMETIC MATERIAL | DOW CORNING TORAY CO., LTD. (JP) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023591-A1 | Phenyl-Containing Organopolysiloxane Composition, Raw Cosmetic Material, and Glossy Cosmetic Material | MITF, XPA, FANCI | PPARG 2286/4885PPARD 3143/4885PPARA 3381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.