SCHEMBL21617266

SCHEMBL21617266

Cc1cccc(Nc2ccc(OCc3ccccc3)cc2C2CC2)c1C(=O)NC(C)C

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PTGES O14684 1/20 0.44
▸ MAOA P21397 2/20 0.43
▸ MAOB P27338 1/20 0.43
▸ CASP3 P42574 1/20 0.40
▸ FFAR1 O14842 3/20 0.40
▸ CTSV O60911 1/20 0.39
▸ CTSL P07711 1/20 0.39
▸ ACACB O00763 2/20 0.39
▸ HTR3A P46098 1/20 0.39
▸ S1PR1 P21453 1/20 0.39
▸ S1PR5 Q9H228 1/20 0.39
▸ GHSR Q92847 1/20 0.38
▸ MTOR P42345 1/20 0.38
▸ PRKDC P78527 1/20 0.38
▸ GPR132 Q9UNW8 1/20 0.38
▸ SIRT2 Q8IXJ6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31504425 1.00 PTGES (0.44) PTGESMAOAMAOBCASP3FFAR1
SCHEMBL31504440 0.93 PTGES (0.45) PTGESMAOAMAOBCTSVCTSL
SCHEMBL21617212 0.93 PTGES (0.45) PTGESMAOAMAOBCTSVCTSL
SCHEMBL21617219 0.90 PTGES (0.43) PTGESMAOAMAOBCASP3CTSV
SCHEMBL31504380 0.90 PTGES (0.43) PTGESMAOAMAOBCASP3CTSV
SCHEMBL21617288 0.88 PTGES (0.41) PTGESMAOAMAOBACACBS1PR1
SCHEMBL21623514 0.88 MAOA (0.42) PTGESMAOAMAOBS1PR1S1PR5
SCHEMBL31504402 0.88 PTGES (0.41) PTGESMAOAMAOBACACBS1PR1
SCHEMBL23308016 0.76 CNR2 (0.42) GPR132
SCHEMBL23308005 0.75 ALDH1A1 (0.45) MAOBCTSVCTSLSIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3820850-B1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2026-04-01 — — EP disclosed
US-12421206-B2 Aryl-n-aryl derivatives for treating a RNA virus infection ABIVAX (FR) 2025-09-23 — — US disclosed
EP-3820850-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-05-19 — — EP disclosed
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-04-29 — — US disclosed
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-04-29 — — US disclosed
WO-2020011816-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2020-01-16 — — WO disclosed
WO-2020011816-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2020-01-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12421206-B2 Aryl-n-aryl derivatives for treating a RNA virus infection NSUN3, CBR3, C1R PTGES 3685/4885MAOA 1648/4885MAOB 2297/4885
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION NSUN3, CBR3, C1R PTGES 3685/4885MAOA 1648/4885MAOB 2297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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