Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | CCR6 | P51684 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.77 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | ADCY1 | Q08828 | 4/20 | 0.58 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12768294 | 0.87 | KDM4E (1.00) | HTTTDP1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL4740831 | 0.76 | SMN1; SMN2 (0.62) | HTTTDP1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL20598356 | 0.74 | ADCY1 (1.00) | HTTTDP1SMN1; SMN2CCR6KDM4E | |
| SCHEMBL1387329 | 0.73 | KDM4E (0.65) | HTTTDP1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL15774288 | 0.73 | KDM4E (0.57) | HTTTDP1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL330637 | 0.72 | LMNA (0.56) | HTTTDP1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL8722458 | 0.72 | KDM4E (0.64) | HTTTDP1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL4737640 | 0.71 | KDM4E (0.63) | HTTTDP1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL7695319 | 0.71 | MAPT (0.57) | HTTTDP1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL20598390 | 0.70 | ADCY1 (1.00) | HTTTDP1SMN1; SMN2POLBCCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295890-A1 | GLYCOSAMINOGLYCAN INHIBITORS | Zacharon Pharmaceutical, Inc. (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2011082175-A2 | GLYCOSAMINOGLYCAN INHIBITORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295890-A1 | GLYCOSAMINOGLYCAN INHIBITORS | CSGALNACT1, FUT5, ST3GAL3 | HTT 2106/4885TDP1 3893/4885SMN1; SMN2 4368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.