Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21518421 | 1.00 | LMNA (0.41) | LMNAMEN1KMT2ABLMAPEX1 | |
| SCHEMBL21787552 | 0.80 | LMNA (0.43) | LMNAMEN1KMT2ABLMAPEX1 | |
| SCHEMBL19025436 | 0.80 | GRIA4 (0.36) | SLC22A6GRIA1 | |
| SCHEMBL21623881 | 0.79 | SLC22A6 (0.34) | SLC22A6GRIA1 | |
| SCHEMBL21518425 | 0.79 | SLC22A6 (0.34) | SLC22A6GRIA1 | |
| SCHEMBL10708540 | 0.77 | SLC22A6 (0.43) | LMNABLMSLC22A6GRIA1 | |
| SCHEMBL21518366 | 0.76 | KDM4E (0.34) | LMNAKDM4ESLC22A6GRIA1HIF1A | |
| SCHEMBL21623880 | 0.76 | KDM4E (0.34) | LMNAKDM4ESLC22A6GRIA1HIF1A | |
| SCHEMBL27658493 | 0.75 | SLC22A6 (0.42) | LMNABLMSLC22A6GRIA1 | |
| SCHEMBL21623898 | 0.74 | CASP7 (0.41) | LMNAMEN1KMT2ABLMADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3824009-A1 | IONICALLY HYDROPHILIZED POLYISOCYANATES WITH IMPROVED DRYING | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-05-26 | — | — | EP | disclosed |
| WO-2020016116-A1 | IONICALLY HYDROPHILIZED POLYISOCYANATES WITH IMPROVED DRYING | COVESTRO DEUTSCHLAND AG (DE) | 2020-01-23 | — | — | WO | disclosed |