Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21623902 | 0.80 | LMNA (0.41) | LMNAMEN1KMT2ABLMAPEX1 | |
| SCHEMBL21518421 | 0.80 | LMNA (0.41) | LMNAMEN1KMT2ABLMAPEX1 | |
| SCHEMBL14134835 | 0.77 | KISS1R (0.38) | ADRB2ADRB1KDM4E | |
| SCHEMBL4594420 | 0.77 | SLC22A6 (0.31) | — | |
| SCHEMBL10278439 | 0.76 | HDAC7 (0.31) | — | |
| SCHEMBL23267902 | 0.76 | LMNA (0.31) | LMNAKDM4E | |
| SCHEMBL15509647 | 0.75 | ADRB2 (0.47) | ADRB2ADRB1ADRB3CYP2D6PTGS1 | |
| SCHEMBL5085551 | 0.75 | SLC22A6 (0.30) | LMNAMEN1KMT2ABLMKDM4E | |
| SCHEMBL26306291 | 0.75 | KDM4E (0.45) | LMNAMEN1KMT2AKDM4E | |
| SCHEMBL14590743 | 0.75 | SLC22A6 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246344-A1 | Biological buffers with wide buffering ranges | DALY THOMAS (US) | 2021-08-12 | — | — | US | disclosed |
| US-20200071582-A1 | Biological Buffers with Wide Buffering Ranges | TPAT IP LLC | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071582-A1 | Biological Buffers with Wide Buffering Ranges | PEF1, SLC7A1, PLPBP | LMNA 1639/4885MEN1 9/4885KMT2A 1937/4885 |
| US-20210246344-A1 | Biological buffers with wide buffering ranges | PEF1, SLC7A1, PLPBP | LMNA 1653/4885MEN1 9/4885KMT2A 1967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.