Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | GABRP | O00591 | 1/20 | 0.57 |
| ▸ | GABRD | O14764 | 1/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.57 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.57 |
| ▸ | GABRE | P78334 | 1/20 | 0.57 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.57 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.57 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14698338 | 0.91 | APEX1 (0.59) | TRPV1HPGDTP53GLAAPEX1 | |
| SCHEMBL21623922 | 0.90 | APEX1 (0.58) | TRPV1HPGDTP53GLAAPEX1 | |
| SCHEMBL30520585 | 0.90 | APEX1 (0.58) | TRPV1HPGDTP53GLAAPEX1 | |
| Nonanoate SCHEMBL29822484 | 0.87 | CYP1A2 (0.66) | TRPV1HPGDTP53ALDH1A1CYP1A2 | |
| SCHEMBL15329262 | 0.87 | ESRRG (0.60) | HPGDLMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL898313 | 0.85 | PTPN7 (0.54) | HPGDALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6567204 | 0.85 | TRPV1 (0.53) | TRPV1HPGDTP53GLAAPEX1 | |
| SCHEMBL5681720 | 0.85 | ERCC1 (0.69) | TRPV1 | |
| SCHEMBL30386504 | 0.84 | APEX1 (0.56) | TRPV1HPGDTP53GLAAPEX1 | |
| SCHEMBL899105 | 0.84 | PTPN7 (0.53) | HPGDALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3355719-B1 | USE OF SOME HYDROXYBENZOIC ACID AMIDES FOR MASKING UNPLEASANT TASTE | SYMRISE AG (DE) | 2020-08-19 | — | — | EP | claimed |
| EP-3470464-A1 | LAYER COMPOSITIONS WITH IMPROVED ELECTRICAL PARAMETERS COMPRISING PEDOT/PSS AND A STABILIZER | Heraeus Deutschland GmbH & Co KG (DE) | 2019-04-17 | — | — | EP | claimed |
| US-20180311132-A1 | USE OF CERTAIN HYDROXYBENZOIC ACID AMIDES FOR MASKING UNPLEASANT TASTE IMPRESSIONS | SYMRISE AG (DE) | 2018-11-01 | — | — | US | claimed |
| EP-3355719-A1 | USE OF CERTAIN HYDROXYBENZOIC ACID AMIDES FOR MASKING UNPLEASANT TASTE IMPRESSIONS | Symrise AG (DE) | 2018-08-08 | — | — | EP | claimed |
| EP-2008530-B1 | Aroma composition for reducing or suppressing unwanted bitter and astringent impressions | SYMRISE AG (DE) | 2011-01-19 | — | — | EP | claimed |
| US-20080317923-A1 | AROMA COMPOSITION FOR REDUCING OR SUPPRESSING AN UNDESIRED BITTER, ASTRINGENT IMPRESSION | SYMRISE GMBH & CO. KG (DE) | 2008-12-25 | — | — | US | claimed |
| EP-2001448-A2 | FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE | Cadbury Adams USA LLC (US) | 2008-12-17 | — | — | EP | claimed |
| WO-2007089652-A2 | FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE | CADBURY ADAMS USA LLC (US) | 2007-08-09 | — | — | WO | claimed |
| US-20070178123-A1 | FLAVOR-ENHANCING COMPOSITIONS, METHOD OF MANUFACTURE, AND METHODS OF USE | KRAFT FOODS GLOBAL BRANDS LLC | 2007-08-02 | — | — | US | claimed |
| US-12414977-B2 | Method of administering seaberry and saw palmetto extracts to inhibit 5α-reductase activity | ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) | 2025-09-16 | — | — | US | disclosed |
| US-20250268972-A1 | 5a-REDUCTASE INHIBITOR | ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) | 2025-08-28 | — | — | US | disclosed |
| US-20230139835-A1 | ALLULOSE IN CRYSTALLINE FORM | SAVANNA INGREDIENTS GMBH (DE) | 2023-05-04 | — | — | US | disclosed |
| EP-4103575-A1 | ALLULOSE IN CRYSTALLINE FORM | Savanna Ingredients GmbH (DE) | 2022-12-21 | — | — | EP | disclosed |
| US-20220370539-A1 | 5a-REDUCTASE INHIBITOR | ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) | 2022-11-24 | — | — | US | disclosed |
| US-20080317923-A1 | AROMA COMPOSITION FOR REDUCING OR SUPPRESSING AN UNDESIRED BITTER, ASTRINGENT IMPRESSION | SYMRISE GMBH & CO. KG (DE) | 2008-12-25 | — | — | US | disclosed |
| US-20080227867-A1 | USE OF 4-HYDROXYCHALCONE DERIVATIVES FOR MASKING AN UPLEASANT TASTE | SYMRISE GMBH & CO. KG (DE) | 2008-09-18 | — | — | US | disclosed |
| US-20080214675-A1 | Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste | SYMRISE GMBH & CO. KG (DE) | 2008-09-04 | — | — | US | disclosed |
| US-20080214675-A1 | Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste | SYMRISE GMBH & CO. KG (DE) | 2008-09-04 | — | — | US | disclosed |
| US-20080214675-A1 | Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste | SYMRISE GMBH & CO. KG (DE) | 2008-09-04 | — | — | US | disclosed |
| US-20070178123-A1 | FLAVOR-ENHANCING COMPOSITIONS, METHOD OF MANUFACTURE, AND METHODS OF USE | KRAFT FOODS GLOBAL BRANDS LLC | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180311132-A1 | USE OF CERTAIN HYDROXYBENZOIC ACID AMIDES FOR MASKING UNPLEASANT TASTE IMPRESSIONS | FAM222B, FAM83B, CDY1; CDY1B | TRPV1 474/4885HPGD 3261/4885TP53 3486/4885 |
| US-20080227867-A1 | USE OF 4-HYDROXYCHALCONE DERIVATIVES FOR MASKING AN UPLEASANT TASTE | TAS2R45, TAS2R43, TAS2R30 | TRPV1 76/4885HPGD 1711/4885TP53 3490/4885 |
| US-20230139835-A1 | ALLULOSE IN CRYSTALLINE FORM | SI, SORD, NOTUM | TRPV1 1272/4885HPGD 2915/4885TP53 2099/4885 |
| US-20080214675-A1 | Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste | TAS1R1, TAS2R1, TAS1R2 | TRPV1 142/4885HPGD 1055/4885TP53 3168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.