Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14698338 | 0.87 | APEX1 (0.59) | HPGDLMNAALDH1A1ALOX15APEX1 | |
| SCHEMBL21623922 | 0.86 | APEX1 (0.58) | HPGDLMNAALDH1A1ALOX15APEX1 | |
| SCHEMBL30520585 | 0.86 | APEX1 (0.58) | HPGDLMNAALDH1A1ALOX15APEX1 | |
| SCHEMBL898978 | 0.85 | HPGD (0.47) | HPGDLMNAPOLBKMT2AMAPT | |
| SCHEMBL21623928 | 0.81 | ERCC1 (0.63) | ALOX15APEX1ALOX5 | |
| SCHEMBL30519963 | 0.81 | ERCC1 (0.63) | ALOX15APEX1ALOX5 | |
| SCHEMBL24402990 | 0.79 | ALOX5 (0.60) | HPGDLMNAPOLBKMT2AGAA | |
| SCHEMBL30686688 | 0.79 | ALOX5 (0.60) | HPGDLMNAPOLBKMT2AGAA | |
| SCHEMBL2853316 | 0.79 | ALDH1A1 (0.52) | HPGDKMT2AMAPTGAAKDM4E | |
| SCHEMBL1031773 | 0.78 | TRPV1 (0.59) | HPGDLMNAALDH1A1ALOX15APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911172-A1 | COMBINATION REMEDY | Symrise AG (DE) | 2021-11-24 | — | — | EP | disclosed |
| EP-3823455-A1 | COMPOSITION FOR SUBSTITUTING SUGAR IN BAKED GOODS | Symrise AG (DE) | 2021-05-26 | — | — | EP | disclosed |
| WO-2020147977-A1 | COMBINATION REMEDY | SYMRISE AG (DE) | 2020-07-23 | — | — | WO | disclosed |
| WO-2020015816-A1 | COMPOSITION FOR SUBSTITUTING SUGAR IN BAKED GOODS | SYMRISE AG (DE) | 2020-01-23 | — | — | WO | disclosed |